Pharmacy Tech Pay

O'Fallon vs St. Louis: Pharmacy Technician Salary (2026)

Compare pharmacy technician salaries between O'Fallon, MO and St. Louis, MO. All figures are 2026 estimates projected from BLS 2025 data.

O'Fallon, MO
$39,841
$19.16/hr
St. Louis, MO
$47,680
$22.92/hr

Side-by-Side Comparison

MetricO'Fallon, MOSt. Louis, MO
Median Salary$39,841$47,680
Hourly Rate$19.16$22.92
Entry Level (P10)$30,528$37,979
25th Percentile$32,034$39,308
75th Percentile$43,347$50,812
Top Earner (P90)$54,879$61,925
Total Employed224,980
Side-by-side bar chart comparing O'Fallon ($39,841) and St. Louis ($47,680) pharmacy technician salaries.O'FallonSt. LouisMedian Salary$39,841$47,680Entry Level (P10)$30,528$37,979Top Earner (P90)$54,879$61,925US Median $48,239

Verdict

St. Louis, MO offers better overall compensation for pharmacy technicians, winning 4 out of 4 metrics compared to O'Fallon.

The salary gap between O'Fallon and St. Louis is $7,839 (19.68%). St. Louis's median is -1.16% compared to the US national median of $48,239.

Salary Range Comparison

The full salary range (10th to 90th percentile) in O'Fallon spans $24,351,St. Louis spans $23,946. O'Fallon has a wider pay range, meaning more potential for high earners but also more variation.

O'Fallon
P10 (Entry)$30,528
P25$32,034
Median$39,841
P75$43,347
P90 (Top)$54,879
St. Louis
P10 (Entry)$37,979
P25$39,308
Median$47,680
P75$50,812
P90 (Top)$61,925

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, St. Louis ($50,143 effective) pays 12.77% more than O'Fallon ($44,465 effective).

O'Fallon
Nominal: $39,841
CoL Index: 89.6
Adjusted: $44,465
St. Louis
Nominal: $47,680
CoL Index: 95.088
Adjusted: $50,143

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose O'Fallon if…

  • You prefer the Missouri area and lifestyle

Choose St. Louis if…

  • Higher median salary ($47,680/year)
  • Better top-earner potential ($61,925)
  • Larger job market (4,980 employed)
  • Better purchasing power (CoL-adjusted: $50,143)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, pharmacy technician salaries in O'Fallon grew 14.0% from 2024 to 2025, compared to 33.5% growth in St. Louis over the same period.

O'Fallon, MO

+14.0%

$33,134 (2024) → $37,785 (2025)

St. Louis, MO

+33.5%

$33,880 (2019) → $45,220 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays pharmacy technicians more: O'Fallon or St. Louis?

St. Louis has a higher median pharmacy technician salary at $47,680/year, compared to O'Fallon at $39,841/year — a difference of $7,839 (19.68%).

What is the hourly rate difference between O'Fallon and St. Louis?

O'Fallon pharmacy technicians earn $19.16/hr while St. Louis hygienists earn $22.92/hr (2026 est.).

Should I relocate from O'Fallon to St. Louis as a pharmacy technician?

Consider more than just salary when comparing O'Fallon and St. Louis. Factor in cost of living (CoL-adjusted: O'Fallon = $44,465, St. Louis = $50,143), job availability (22 vs 4,980 employed), commute, and career growth potential.

What do entry-level pharmacy technicians earn in O'Fallon vs St. Louis?

Entry-level (10th percentile) pharmacy technicians earn $30,528 in O'Fallon and $37,979 in St. Louis. The St. Louis area offers higher starting salaries.

Related Comparisons

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Written by Emily Tran, PharmD

Career Analyst

Emily Tran has over 8 years of experience as a pharmacy technician. She specializes in medication therapy management. Her experience includes working in community pharmacies.

Clinically reviewed by David Kim, CPhTData verified by Fatima Hassan, CPhT

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.44% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Emily Tran, PharmD, a licensed pharmacy technician with 10+ years of clinical experience. · View source data at BLS.gov